Sleep Apnea and Stroke Research

Sleep Apnea and Stroke Research

Stroke Program faculty investigate the relationship between sleep disorders and stroke and stroke outcome, and the treatment of sleep apnea in post-stroke patients. Two ongoing NIH-funded projects investigate the epidemiology of sleep apnea after stroke and health disparities related to sleep apnea after stroke.

The Epidemiology of Sleep Apnea in a Bi-ethnic Stroke Population

This project seeks to understand the influence of a very frequent risk factor, sleep apnea, on ischemic stroke in the largest and fastest growing US minority population, Hispanics.

PI: Lisabeth/Brown. Funding: R01 HL098065.

Sleep Apnea Health Disparities in Mexican-American Stroke Patients

This project seeks to investigate health disparities related to sleep apnea in Hispanic stroke patients in Corpus Christi, Texas.

PI: Lisabeth/Brown. Funding: R01 NS070941

Positional Therapy for Ischemic Stroke Patients with Sleep Apnea

This pilot clinical trial showed that positional therapy had modest effects on sleep apnea severity in patients with stroke.

PI: Brown. Funding: MICHR Pilot and Collaborative Grant Program

EPAP for Stroke Patients with Sleep Apnea

This pilot clinical trial tests the effects of expiratory positive pressure (EPAP) on sleep apnea severity in ischemic stroke patients.

PI: Brown. Funding: MICHR Seed Grant.

Sleep Apnea Treatment After Stroke (SATS) trial

This pilot randomized, sham-controlled trial tested the feasibility of CPAP for stroke patients with sleep apnea.

PI: Brown. Funding: K23 NS051202

Hypoglossal Nerve Function in Ischemic Stroke Patients with Sleep Apnea

This study compared hypoglossal nerve conduction studies in stroke patients with and without sleep apnea. It provided novel physiological data about the pathophysiology of sleep apnea in stroke patients.

PI: Brown.

Shift Work and Stroke in the Nurses’ Health Study

This project was designed to evaluate for an association between shift work and incident stroke in the Nurses’ Health Study cohort.